Article Text
Letter
Serum pro-hepcidin: measuring active hepcidin or a non-functional precursor?
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We read with great interest the paper “Pro-hepcidin: expression and cell specific localisation in the liver and its regulation in hereditary haemochromatosis, chronic renal insufficiency, and renal anaemia” (Gut 2004;53:735–43) .
We have two observations. Firstly it was shown that pro-hepcidin and hepcidin were colocalised within the liver and in Hep-G cells. However, it was not possible, using serum ELISA, to identify the C terminus of …