You are here

Article Text

Article menu
Download PDFPDF
Letter
Laterally spreading tumour in which interstitial deletion of β-catenin exon 3 was detected
  1. K Nosho1,
  2. H Yamamoto1,
  3. M Mikami1,
  4. T Takahashi1,
  5. Y Adachi1,
  6. T Endo1,
  7. K Hirata2,
  8. K Imai3,
  9. Y Shinomura3
  1. 1First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan
  2. 2First Department of Surgery, Sapporo Medical University, Sapporo, Japan
  3. 3First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan
  1. Correspondence to:
    Dr K Nosho
    First Department of Internal Medicine, Sapporo Medical University, S-1, W-16, Chuo-ku, Sapporo 060-8543, Japan; noshosapmed.ac.jp

https://doi.org/10.1136/gut.2005.075184

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Laterally spreading tumours (LSTs) of the colon and rectum are defined as lesions greater than 10 mm in diameter with a low vertical axis that extend laterally along the luminal wall.1 As most LSTs remain as adenomas or early invasive cancers, LSTs have been thought to have relatively little malignant potential. LSTs are divided into two macroscopic subtypes: flat (F)-type, which is composed of superficially spreading lesions with flat and smooth surfaces, and granular (G)-type, which is composed of superficially spreading aggregates of nodules.2 Despite distinctive biological behaviours of LSTs, only a few genetic alterations have been reported, such as K-ras and p53 mutations3,4 and cyclooxygenase 2 overexpression.5

    A 62 year old Japanese woman was referred to our hospital for treatment of a colonic tumour. Colonoscopy in our hospital showed an F-type LST with a central depression surrounded by a flat elevated area with a smooth surface in the …

    View Full Text

    Footnotes

    • Conflict of interest: None declared.