We were very interested in the recent article by Moschen et al on activation of the RANKL/OPG system in inflammatory bowel disease (IBD) (Gut 2005;54:479–87). Until recently, osteoporosis secondary to gastrointestinal diseases was mainly considered a direct consequence of malabsorption.^1,2 The article of Moschen et al and a previous one of our group on bone loss in coeliac disease,³ a disorder similarly characterised by …