We refer to the recent paper by Durno et al “Family history and molecular features of children, adolescents, and young adults with colorectal carcinoma” (Gut 2005;54:1146–50).

Among other patients with early onset colorectal cancer (CRC), the authors discuss a girl with CRC onset at the age of 12 years, and a subsequent second primary tumour (glioblastoma). This patient appears to be the sister of a male Turcot syndrome patient described …