Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: a randomised controlled pilot trial

E Furrie; S Macfarlane; A Kennedy; J H Cummings; S V Walsh; D A O’Neil; G T Macfarlane

doi:10.1136/gut.2004.044834

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Inflammatory bowel disease

Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: a randomised controlled pilot trial

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	Abstract	Full	Pdf
Jan 2005	501	577	504
Feb 2005	209	454	279
Mar 2005	148	322	178
Apr 2005	90	199	111
May 2005	58	174	86
Jun 2005	47	159	63
Jul 2005	46	95	43
Aug 2005	39	89	65
Sep 2005	49	101	47
Oct 2005	47	121	56
Nov 2005	36	104	61
Dec 2005	31	66	43
Jan 2006	57	33	29
Feb 2006	19	128	98
Mar 2006	35	150	132
Apr 2006	25	95	93
May 2006	21	119	82
Jun 2006	31	94	76
Jul 2006	28	82	55
Aug 2006	32	86	53
Sep 2006	33	88	63
Oct 2006	35	128	70
Nov 2006	31	195	72
Dec 2006	31	80	50
Jan 2007	38	115	101
Feb 2007	33	107	57
Mar 2007	41	96	76
Apr 2007	58	22	32
May 2007	46	35	37
Jun 2007	33	40	42
Jul 2007	32	38	31
Aug 2007	50	29	25
Sep 2007	49	35	47
Oct 2007	52	28	40
Nov 2007	40	31	35
Dec 2007	36	29	35
Jan 2008	26	41	37
Feb 2008	57	27	33
Mar 2008	42	27	22
Apr 2008	67	21	23
May 2008	44	17	18
Jun 2008	45	16	33
Jul 2008	56	10	14
Aug 2008	67	13	11
Sep 2008	43	16	22
Oct 2008	58	21	20
Nov 2008	45	10	17
Dec 2008	37	7	13
Jan 2009	52	15	19
Feb 2009	48	19	22
Mar 2009	64	22	19
Apr 2009	46	18	17
May 2009	44	11	16
Jun 2009	49	10	15
Jul 2009	51	13	16
Aug 2009	38	4	3
Sep 2009	48	13	18
Oct 2009	61	11	13
Nov 2009	64	13	21
Dec 2009	99	6	10
Jan 2010	42	6	13
Feb 2010	47	9	10
Mar 2010	55	17	21
Apr 2010	47	20	10
May 2010	71	11	13
Jun 2010	110	10	8
Jul 2010	66	8	12
Aug 2010	102	7	9
Sep 2010	70	10	8
Oct 2010	72	6	10
Nov 2010	85	13	9
Dec 2010	77	12	12
Jan 2011	72	21	14
Feb 2011	81	17	11
Mar 2011	98	30	22
Apr 2011	68	20	10
May 2011	90	28	15
Jun 2011	85	20	14
Jul 2011	67	17	8
Aug 2011	97	21	7
Sep 2011	100	12	7
Oct 2011	119	18	9
Nov 2011	95	43	18
Dec 2011	51	97	17
Jan 2012	86	77	31
Feb 2012	67	71	24
Mar 2012	62	124	22
Apr 2012	70	100	35
May 2012	67	94	32
Jun 2012	74	102	33
Jul 2012	68	64	20
Aug 2012	78	103	26
Sep 2012	52	84	22
Oct 2012	72	112	27
Nov 2012	95	54	33
Dec 2012	86	24	24
Jan 2013	73	15	20
Feb 2013	76	27	25
Mar 2013	80	24	22
Apr 2013	89	43	32
May 2013	62	24	26
Jun 2013	62	14	19
Jul 2013	60	21	18
Aug 2013	48	23	12
Sep 2013	73	31	18
Oct 2013	94	25	29
Nov 2013	68	34	23
Dec 2013	65	22	17
Jan 2014	66	28	28
Feb 2014	54	23	19
Mar 2014	71	22	18
Apr 2014	77	33	27
May 2014	66	52	24
Jun 2014	58	18	17
Jul 2014	64	31	18
Aug 2014	54	34	24
Sep 2014	47	18	8
Oct 2014	84	34	29
Nov 2014	66	25	15
Dec 2014	64	21	4
Jan 2015	52	32	21
Feb 2015	259	226	27
Mar 2015	404	361	27
Apr 2015	359	318	22
May 2015	409	407	28
Jun 2015	427	344	28
Jul 2015	336	299	28
Aug 2015	348	305	26
Sep 2015	134	56	15
Oct 2015	74	37	18
Nov 2015	81	50	27
Dec 2015	103	50	7
Jan 2016	143	92	24
Feb 2016	160	108	25
Mar 2016	87	48	20
Apr 2016	101	65	13
May 2016	86	38	22
Jun 2016	95	59	14
Jul 2016	115	70	15
Aug 2016	110	67	13
Sep 2016	132	64	19
Oct 2016	100	17	13
Nov 2016	58	15	11
Dec 2016	96	16	11
Jan 2017	121	19	13
Feb 2017	42	9	22
Mar 2017	41	26	15
Apr 2017	45	44	32
May 2017	21	45	18
Jun 2017	42	52	20
Jul 2017	63	37	11
Aug 2017	87	40	19
Sep 2017	103	49	15
Oct 2017	150	58	18
Nov 2017	135	59	31
Dec 2017	163	79	19
Jan 2018	105	53	19
Feb 2018	112	54	20
Mar 2018	111	53	26
Apr 2018	250	156	19
May 2018	147	98	19
Jun 2018	182	84	26
Jul 2018	107	53	20
Aug 2018	166	126	26
Sep 2018	170	130	27
Oct 2018	165	113	39
Nov 2018	188	130	24
Dec 2018	164	114	13
Jan 2019	155	104	36
Feb 2019	99	66	15
Mar 2019	97	59	36
Apr 2019	153	73	45
May 2019	119	46	39
Jun 2019	61	34	19
Jul 2019	81	44	35
Aug 2019	71	44	28
Sep 2019	78	55	18
Oct 2019	113	79	24
Nov 2019	129	100	30
Dec 2019	137	112	18
Jan 2020	124	94	19
Feb 2020	97	69	20
Mar 2020	166	138	41
Apr 2020	89	62	20
May 2020	123	82	30
Jun 2020	102	72	32
Jul 2020	92	69	32
Aug 2020	85	57	31
Sep 2020	138	114	16
Oct 2020	148	112	33
Nov 2020	87	56	26
Dec 2020	95	68	28
Jan 2021	83	67	18
Feb 2021	118	95	31
Mar 2021	133	116	30
Apr 2021	106	81	31
May 2021	90	86	22
Jun 2021	91	88	39
Jul 2021	56	56	23
Aug 2021	34	34	21
Sep 2021	37	37	36
Oct 2021	73	53	47
Nov 2021	97	53	30
Dec 2021	93	65	22
Jan 2022	93	59	36
Feb 2022	211	194	21
Mar 2022	118	84	50
Apr 2022	80	69	29
May 2022	106	100	41
Jun 2022	77	52	28
Jul 2022	92	68	15
Aug 2022	131	105	18
Sep 2022	77	61	24
Oct 2022	68	54	23
Nov 2022	95	76	38
Dec 2022	120	94	20
Jan 2023	99	78	19
Feb 2023	79	60	24
Mar 2023	110	84	28
Apr 2023	75	41	36
May 2023	118	74	46
Jun 2023	71	62	13
Jul 2023	74	47	20
Aug 2023	82	58	18
Sep 2023	139	113	18
Oct 2023	284	238	35
Nov 2023	520	500	24
Dec 2023	365	18	5
Jan 2024	241	5	1
Feb 2024	253	6	6
Mar 2024	427	18	8
Total	22807	16732	7177

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