Statistics from Altmetric.com
Renal disease secondary to chronic hepatitis C virus (HCV) infection is infrequent but often life threatening and difficult to treat. Management is directed towards eradication of the virus. Combination therapy with interferon α or pegylated interferon α and ribavirin has been used successfully to induce recovery from membranoproliferative glomerulonephritis (MPGN), cryoglobulinaemia, and vasculitis, if viral clearance is achieved.1–8 Unfortunately, symptoms recur in the absence of a sustained virological response. Long term suppressive maintenance therapy may be an alternative, but has not been reported previously.
A 46 year old man with HCV genotype 4 was referred to our institution for evaluation of chronic HCV infection (CHC) and nephrotic syndrome. Initial investigations revealed proteinuria (+++) and haematuria (+++) with dysmorphic red cells on urinalysis. Haemoglobin level (Hb) was 136 g/l, …
Conflict of interest: None declared.
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.