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Prognostic value of the lymph node ratio in node positive colon cancer
  1. M De Ridder,
  2. V Vinh-Hung,
  3. Y Van Nieuwenhove,
  4. A Hoorens,
  5. A Sermeus,
  6. G Storme
  1. Academic Hospital of the Free University of Brussels, Oncology Centre, Brussels, Belgium
  1. Correspondence to:
    Professor M De Ridder
    Academic Hospital of the Free University of Brussels, Oncology Centre, Laarbeeklaan 101, B-1090 Brussels, Belgium; Mark.Deridder{at}

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Surgery is the primary treatment of non-metastatic colon cancer. En bloc removal of the colon with its associated mesenteric lymph nodes is essential. However, the number of lymph nodes reported with colectomy varies widely and may be a result of variation in the actual number of regional lymph nodes, surgical technique, or the thoroughness of the pathologist in finding lymph nodes. The number of lymph node metastases is an important negative prognostic factor and is used in stratification schemes for clinical trials.1

Recent studies have emphasised the fact that examining a greater number of nodes increases the likelihood of correct staging and is associated with better survival, after controlling …

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  • This work was supported by grants from “Foundation against Cancer, foundation of public interest”, and the “Scientific Fund W Gepts AZ-VUB”.

  • Conflict of interest: None declared.

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