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Influence of obesity on the risk of developing colon cancer
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  • Published on:
    Chronic sub-clinical bowel inflammation may explain increased risk of colorectal cancer in the obese
    • Biku J John, Registrar
    • Other Contributors:
      • Al Mutaz Abulafi, Andrew Poullis, Michael Anthony Mendall

    Dear Editor,

    We read with interest the recent articles on obesity, inflammation and Colorectal cancer (CRC).1,2,3 Although insulin resistance is the most widely accepted underlying mechanism explaining the association between obesity and CRC, recent evidence suggests that the effects of obesity on the immune system in general and specifically on the gut may play a role. We propose that obesity predisposes to CR...

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    Conflict of Interest:
    None declared.