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Autoimmune hepatitis triggered by hepatitis A
  1. G Singh,
  2. S Palaniappan,
  3. O Rotimi,
  4. P J Hamlin
  1. Centre for Digestive Diseases, The General Infirmary at Leeds, Leeds, UK
  1. Correspondence to:
    G Singh
    Leeds General Infirmary, Great George St, Leeds LS1 3EX, UK; drgurjitsingh{at}

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We describe a case of autoimmune hepatitis triggered by an acute hepatitis A infection. A young woman presented with a 10 day history of nausea and dark urine having returned from Tunisia a month previously. She had marked transaminitis. Viral serology demonstrated positive hepatitis A immunoglobulin M. Other viral serology was negative. Autoantibody screening revealed positive antismooth muscle antibodies (titre 1 in 80) but negative antinuclear (ANA), antimitochondrial, and antiliver, kidney and pancreas (LKM) antibodies. Immunoglobulin levels revealed normal IgA and IgG levels …

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  • Competing interests: None.

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