Article Text

Download PDFPDF
The prevalence of small intestinal bacterial overgrowth in irritable bowel syndrome: IBS vs healthy controls (not historical definitions)
  1. M Pimentel
  1. Dr M Pimentel, GI Motility Program, Cedars-Sinai Medical Center, 8730 Alden Drive, Suite 225E, Los Angeles, CA 90048, USA; pimentelm{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

The potential role of small intestinal bacterial overgrowth (SIBO) in irritable bowel syndrome (IBS) has been strongly debated in the recent literature. Much of the controversy surrounding SIBO as a potential factor in IBS is due to the methods used in diagnosing SIBO. In a recent systematic literature review,1 we evaluated all diagnostic tests for the determination of SIBO. In this review, no test was found to be accurate. In fact, even culture was not a valid gold standard.

Culture of the small bowel for the identification of SIBO suffers from a number of flaws. Some challenges include: (1) maintaining an …

View Full Text


  • Competing interests: None.

Linked Articles

  • Letter
    M Simrén I Posserud P-O Stotzer E S Björnsson H Abrahamsson