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Fatigue in non-alcoholic fatty liver disease: is there a role for hypothyroidism
  1. E Kalaitzakis
  1. Dr E Kalaitzakis, Section of Gastroenterology and Hepatology, Department of Internal Medicine, Sahlgrenska University Hospital, 413 45 Gothenburg, Sweden; evangelos.kalaitzakis{at}

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I read with great interest the article by Newton et al (Gut 2008;57:807–13) concerning fatigue in patients with non-alcoholic fatty liver disease (NAFLD). The authors enrolled 156 consecutive patients with histologically proven NAFLD in whom fatigue, depression, daytime somnolence, and health-related quality of life were assessed by means of validated questionnaires. Physical activity was also evaluated by accelerometry and results were compared to those of age-, sex-, and body mass index-matched healthy controls as well as patients with primary biliary cirrhosis. Fatigue was found to …

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  • Competing interests: None.

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