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We read with great interest the article by Trak-Smayra and colleagues1 showing that serum free haemoglobin subunits correlated positively with severity of liver lesions in non-alcoholic fatty liver disease (NAFLD) and may serve as a biomarker for the disease. However, the detail relationship between serum haemoglobin concentrations and NAFLD has not been clearly clarified.
Recently, we conducted a cross-sectional study to analysis the association of serum haemoglobin concentration with NAFLD. We included 8985 employees (6101 men, mean age 45.7 years) of the Zhenhai Refining & Chemical Company Ltd. (Ningbo, China) who were attending their annual health examination …
Funding This study was supported by Chinese State Key Project for High-tech (No. 2006AA02A308), National Natural Science Foundation of China (No. 30871154) and Science and Technology Foundation of Zhejiang Province (No. 2008C13027-1).
Competing interests None.
Provenance and peer review Not commissioned; not externally peer reviewed.
LX and C-f Xu contributed equally to this work.