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Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis
  1. E A M Festen1,
  2. P Goyette2,
  3. R Scott3,
  4. V Annese4,
  5. A Zhernakova5,
  6. J Lian2,
  7. C Lefèbvre2,
  8. S R Brant6,
  9. J H Cho7,
  10. M S Silverberg8,
  11. K D Taylor9,
  12. D J de Jong10,
  13. P C Stokkers11,
  14. D Mcgovern11,
  15. O Palmieri4,
  16. J-P Achkar12,
  17. R J Xavier13,
  18. M J Daly14,
  19. R H Duerr3,
  20. C Wijmenga2,
  21. R K Weersma1,
  22. J D Rioux2
  1. 1
    Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
  2. 2
    Laboratory in Genetics and Genomic Medicine of Inflammation, Montreal Heart Institute, Université de Montréal, Montreal, Canada
  3. 3
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
  4. 4
    UU.OO. Gastroenterologia ed Endoscopia Digestiva, Ospedale “Casa Sollievo della Sofferenza”, IRCCS, San Giovanni Rotondo, Italy
  5. 5
    Complex Genetics Section, Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands
  6. 6
    Harvey M and Lyn P Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
  7. 7
    Departments of Medicine and Genetics, Division of Gastroenterology, Inflammatory Bowel Disease (IBD) Center, Yale University, New Haven, Connecticut, USA
  8. 8
    Mount Sinai Hospital IBD Centre, University of Toronto, Toronto, Ontario, Canada
  9. 9
    Medical Genetics Institute and Inflammatory Bowel Disease (IBD) Center, Cedars-Sinai Medical Center, Los Angeles, California, USA
  10. 10
    Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
  11. 11
    Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands
  12. 12
    Center for Inflammatory Bowel Disease, Department of Gastroenterology & Hepatology, Cleveland Clinic, Cleveland, Ohio, USA
  13. 13
    Center for Computational and Integrative Biology and Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Massachusetts, USA
  14. 14
    Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
  1. Dr J D Rioux, Université de Montréal and the Montreal Heart Institute, Research Center, 5000 Bélanger Street, Montreal, Quebec H1T 1C8, Canada; john.david.rioux{at}umontreal.ca

Footnotes

  • Competing interests: None.

  • Funding: This study was made possible by a VICI grant from the Netherlands Organization for Scientific Research (918.66.620) to CW, and an AGIKO-grant from the Netherlands Organization for Scientific Research to EF.

  • ▸ Additional tables are published online only at http://gut.bmj.com/content/vol58/issue6

  • Patient consent: Informed consent was obtained using protocols approved by the local institutional review board in all participating institutions.

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Footnotes

  • Competing interests: None.

  • Funding: This study was made possible by a VICI grant from the Netherlands Organization for Scientific Research (918.66.620) to CW, and an AGIKO-grant from the Netherlands Organization for Scientific Research to EF.

  • ▸ Additional tables are published online only at http://gut.bmj.com/content/vol58/issue6

  • Patient consent: Informed consent was obtained using protocols approved by the local institutional review board in all participating institutions.

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