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Should we refer diminutive polyps to post-CTC polypectomy?
  1. C Hassan1,
  2. P J Pickhardt2,
  3. A Laghi3,
  4. D H Kim2,
  5. A Zullo1
  1. 1
    Gastroenterology and Digestive Endoscopy Unit, “Nuovo Regina Margherita” Hospital, Rome
  2. 2
    Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA
  3. 3
    Department of Radiological Sciences, University “Polo Pontino”, Rome, Italy
  1. Correspondence to Dr C Hassan, Gastroenterology and Digestive Endoscopy Unit, “Nuovo Regina Margherita” Hospital, Via Morosini 30, Rome, Italy; cesareh{at}

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We read with interest paper by Graser et al1 comparing CT colonography (CTC) with optical colonoscopy (OC) and other screening tests in an average-risk population. In a series of 311 subjects, the authors described 13 cases of advanced neoplasia (high-grade dysplasia or a villous component) in <10 mm polyps. In detail, seven of these cases occurred in <5 mm adenomas, so that diminutive adenomas accounted for 16% of all of the advanced neoplasia detected in the study, also being more frequent than 6–9 mm advanced adenomas. Such a relatively high rate of advanced neoplasia in <5 …

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  • Competing interests None.

  • Provenance and Peer review Not commissioned; not externally peer reviewed.