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  • Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers

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Colon cancer
Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers

Authors

  1. Correspondence to Dr Alex Duval, INSERM UMRS 938, Equipe ‘Instabilité des Microsatellites et Cancers’, Hôpital Saint-Antoine, 184 rue du Faubourg Saint-Antoine, F75571 Paris cedex 12; alex.duval{at}inserm.fr
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Citation

Svrcek M, Buhard O, Colas C, et al
Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers
Gut 2010;59:1516-1526.

Publication history

  • Received July 31, 2009
  • Accepted July 5, 2010
  • First published October 14, 2010.
Online issue publication 
April 18, 2016

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© 2010, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.