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We read with interest the leading article by Hunt and van Heel on recent advances in coeliac disease (CD) genetics.1 They suggested that further investigation of the coeliac-associated single nucleotide polymorphisms (SNPs) in other populations was needed. Our recent work may help to push this research work in the Chinese population. Here we report on a serological screening for CD in China. CD has been historically considered to be absent in the Far East (China, Japan, Korea, Malaysia, etc.).2 However, since the major known risk factors for CD are common in China, we used serological tests for immunoglobulin G (IgG) antigliadin antibodies (AGAs) and IgA antitissue transglutaminase antibodies (tTGs) to screen for CD in high risk patients,3 …
Competing interests None.
Ethics approval This study was conducted with the approval of the Ethics Committee of Jiangsu Provincial Hospital of TCM.
Patient consent Obtained.
Provenance and peer review Not commissioned; not externally peer reviewed.
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