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In their recent paper, Grazzini and colleagues1 reported a decrease in the positivity of the immunochemical faecal occult blood test (iFOBT) for colorectal cancer screening during the summer period. Their results predict a higher rate of false-negative iFOBT results during the hot season. This effect is likely to be higher for patients with minor neoplastic lesions, where the haemoglobin concentration in faeces is usually lower2 than in patients with …
Competing interests None.
Provenance and peer review Not commissioned; not externally peer reviewed.