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HCCR-1 for detecting small hepatocellular carcinoma latent in a cirrhotic liver: a prospective cohort study
  1. Peng Jirun1,
  2. Guoxin Zhang2,
  3. Seon-Ah Ha3,
  4. Hyun Kee Kim3,
  5. Jinah Yoo3,
  6. Sanghee Kim3,
  7. Jin Zhongtian1,
  8. Cui Zhuqingqing1,
  9. Youn Soo Lee4,
  10. Gi Hwan Gong5,
  11. Joo Hee Yoon5,
  12. Hae Nam Lee5,
  13. Sa Jin Kim5,
  14. Tae Eung Kim5,
  15. Eun Young Song6,
  16. Yun Kyung Lee3,
  17. Yong Gyu Park7,
  18. Jin Woo Kim3,5
  1. 1Department of Surgery, Peking University People's Hospital, Beijing, China
  2. 2Department of Gastroenterology, Nanjing Medical University, Nanjing, P R China
  3. 3Molecular Genetic Laboratory, College of Medicine, The Catholic University of Korea, Seoul, Korea
  4. 4Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea
  5. 5Departments of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea, Seoul, Korea
  6. 6Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea
  7. 7Department of Biostatistics, College of Medicine, The Catholic University of Korea, Seoul, Korea
  1. Correspondence to Professor Jin Woo Kim, Molecular Genetic Laboratory, College of Medicine, The Catholic University of Korea, Seoul 137-040, Korea; jinwoo{at}catholic.ac.kr

http://dx.doi.org/10.1136/gutjnl-2012-301994

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    We read with great interest the leading article by Tremosini and coworkers in Gut (2012 doi:10.1136/gutjnl-2011-301951) on the prospective validation of an immunohistochemical panel (glypican 3, heat shock protein 70 and glutamine synthetase) in liver biopsies for …

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    Footnotes

    • Competing interests None.

    • Patient consent Obtained.

    • Ethics approval This study was conducted with the approval of the St Mary's Hospital Research Ethics Committee, Nanjing Medical University Hospital Ethics Committee, and Peking University People's Hospital Ethics Committee, respectively.

    • Provenance and peer review Not commissioned; externally peer reviewed.