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Lymphocytic oesophagitis, a condition in search of a disease?
  1. Jukka Ronkainen1,
  2. Marjorie M Walker2,
  3. Pertti Aro3,
  4. Tom Storskrubb4,
  5. Nicholas J Talley5,
  6. Zohreen B Ahmed2,
  7. Victoria Salter2,
  8. Michael Vieth6,
  9. Lars Agréus3
  1. 1Primary Health Care Center Tornio, Institute of Health Sciences, University of Oulu, Tornio, Finland
  2. 2Histopathology, Centre for Pathology, Division of Medicine, Imperial College, London, UK
  3. 3Center for Family and Community Medicine, Karolinska Institutet, Stockholm, Sweden
  4. 4Aspstigen 5, Kalix, Sweden
  5. 5Health Callaghan, University of Newcastle, Callaghan, New South Wales, Australia
  6. 6Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany
  1. Correspondence to Dr Marjorie M Walker, Centre for Pathology, Division of Medicine, Imperial College, Histopathology, London, W2 1NY, UK; mm.walker{at}

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There have been conflicting studies on the existence of lymphocytic oesophagitis, first described by Rubio et al in 2006 and characterised by an excess infiltration of intraepithelial lymphocytes (IELs) in the peripapillary fields.1 We therefore read with interest the article by Haque and Genta which states lymphocytic oesophagitis occurs in 0.1% of oesophageal biopsies from a large gastrointestinal pathology practice covering 43 states in the USA.2 Lymphocytic oesophagitis is described in this …

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  • Funding This study was supported by Norrbotten County, Swedish Medical Research Council and Swedish Medical Society, Magtarmsjukas Förbund, and AstraZeneca.

  • Competing interests None.

  • Ethics approval Ethics approval was provided by Umeå University, Sweden Ethics Committee.

  • Provenance and peer review Not commissioned; externally peer reviewed.