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Letter
Authors' response
  1. Margot G F van Lier1,
  2. Anja Wagner2,
  3. Katharina Biermann3,
  4. Elisabeth M H Mathus-Vliegen4,
  5. Ernst J Kuipers1,5,
  6. Monique E van Leerdam1
  1. 1Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
  2. 2Department of Clinical Genetics, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
  3. 3Department of Pathology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
  4. 4Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands
  5. 5Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
  1. Correspondence to M G F van Lier, Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Room Hs-304, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands; m.g.f.vanlier{at}erasmusmc.nl

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We appreciate the comments by Riegert-Johnson et al1 on our manuscript concerning cancer risk and mortality in patients with Peutz–Jeghers syndrome (PJS).2 We fully agree that it is of major importance for the clinical management and surveillance of PJS patients to establish whether their gastrointestinal malignancies are from hamartomas, coexisting adenomas or otherwise normal-appearing mucosa. This is indeed, as Dr Riegert-Johnson and colleagues mention, an issue of debate. Although …

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Footnotes

  • Linked article 238642.

  • Competing interests None.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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