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Original article
Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota
  1. Matteo Serino1,2,
  2. Elodie Luche1,2,
  3. Sandra Gres1,2,
  4. Audrey Baylac3,
  5. Mathieu Bergé3,
  6. Claire Cenac4,
  7. Aurelie Waget1,2,
  8. Pascale Klopp1,2,
  9. Jason Iacovoni1,2,
  10. Christophe Klopp5,
  11. Jerome Mariette5,
  12. Olivier Bouchez6,
  13. Jerome Lluch6,
  14. Francoise Ouarné7,
  15. Pierre Monsan7,8,9,10,
  16. Philippe Valet1,2,
  17. Christine Roques3,
  18. Jacques Amar11,
  19. Anne Bouloumié1,2,
  20. Vassilia Théodorou4,
  21. Remy Burcelin1,2
  1. 1Institut National de la Santé et de la Recherche Médicale (INSERM), Toulouse, France
  2. 2Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut de Maladies Métaboliques et Cardiovasculaires (I2MC), Toulouse Cedex 4, France
  3. 3Université de Toulouse III, UPS, LU49, Adhésion Bactérienne et Formation de Biofilms, Toulouse Cedex 9, France
  4. 4Neuro-Gastroenterology and Nutrition Unit, UMR INRA/EI-Purpan, Toulouse Cedex 3, France
  5. 5Plateforme Bio-informatique Toulouse Genopole®, UBIA INRA, Castanet-Tolosan Cedex, France
  6. 6GENOTOUL Platform, INRA Chemin de Borde-Rouge, Auzeville, France
  7. 7Université de Toulouse III, INSA, UPS, INP, LISBP, Toulouse, France
  8. 8CNRS, UMR5504, Toulouse, France
  9. 9INRA, UMR792 Ingénierie des Systèmes Biologiques et des Procédés, Toulouse, France
  10. 10Institut Universitaire de France, Paris, France
  11. 11Rangueil Hospital, Department of Therapeutics, Toulouse, France
  1. Correspondence to Dr Remy Burcelin, Université Paul Sabatier (UPS), Unité Mixte de Recherche (UMR) 1048, Institut de Maladies Métaboliques et Cardiovasculaires (I2MC), F-31432 Toulouse Cedex 4, France; remy.burcelin{at}inserm.fr

Footnotes

  • See Commentary, p 474

  • Funding This work was supported by grants from Agence Nationale pour la Recherche (ANR) to RB and collaborators (ANR-Florinflam and Transflora); in part, by the European Commission's Seventh Framework programme under grant agreement No 241913 (FLORINASH) to RB and by the Benjamin Delessert Foundation to MS.

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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Footnotes

  • See Commentary, p 474

  • Funding This work was supported by grants from Agence Nationale pour la Recherche (ANR) to RB and collaborators (ANR-Florinflam and Transflora); in part, by the European Commission's Seventh Framework programme under grant agreement No 241913 (FLORINASH) to RB and by the Benjamin Delessert Foundation to MS.

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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