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We thank Dr Braganza1 for the stimulating comments regarding our study.2 Haem-oxygenase-1 (HO-1) is a ubiquitous enzyme and plays an important role in many cell types. We previously demonstrated a protective role for HO-1+ monocytes/macrophages in acute pancreatitis using adoptive peritoneal cell transfers from haemin-treated mice into mice undergoing acute pancreatitis.3 We have not assessed the role or contribution of mast cells in our studies, …
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