Article Text
PostScript
Letter
Altered gut microbiota composition in immune-impaired Nod2−/− mice
Statistics from Altmetric.com
- Microbiome
- genetic predisposition
- bacteroidetes
- high-throughput DNA sequencing
- Crohn's disease
- inflammatory bowel disease
- intestinal bacteria
- immune response
- mucosal immunology
- bacterial interactions
- metagenomics
- carbohydrates
- anaerobic bacterial fermentation
- molecular biology
- mucins
- intestinal microbiology
- inflammatory diseases
- bacterial adherence
- short-chain fatty acids
- bacterial interactions
- trefoil peptides
- IBD
- mucus
- Helicobacter pylori
- acid-related diseases
- non-ulcer dyspepsia
- genetic polymorphisms
- gastric neoplasia
- colonic microflora
- gene mutation
- IBD–genetics
We read with great interest the recently published study by Rehman and colleagues.1 Investigating microbial diversity on faecal and ileal samples from 48 mice using Sanger and 454 techniques, Rehman et al detected increased percentages of Bacteroidetes in the faeces of adult Nod2−/− mice, whereas Firmicutes levels were significantly higher only in the ileum of Nod2−/− mice.
Since we demonstrated that antibiotic …
Footnotes
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.