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Letter
Ischaemic colitis associated with JAK2V617F mutation
  1. J Barbieri1,
  2. H Duboc1,
  3. F Teillet2,
  4. J M Sabate1,
  5. E Peynaud2,
  6. P Jouet1,
  7. B Coffin1
  1. 1Gastroenterology Unit, AP-HP Louis Mourier Hospital and University Denis Diderot Paris VII, Colombes, France
  2. 2Haematology and Immunology Unit, AP-HP Louis Mourier Hospital and University Denis Diderot Paris VII, Colombes, France
  1. Correspondence to Dr H Duboc, Hépato-gastro-enterologie, 178 rue des renouillers, 92700 Colombes, France; henri.duboc{at}lmr.aphp.fr

https://doi.org/10.1136/gutjnl-2011-300396

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    We read with interest the review by Mensink et al1 on gastrointestinal ischaemia. The authors achieved a proper focus regarding the diagnostic tools and treatments of underestimated, complex and delayed diagnoses. As mentioned, the diagnosis of ischaemia is primarily invoked in cases concerning the acute onset of abdominal symptoms in patients with vascular risk factors.1 In that vein, we would like to report the first description of an acute ischaemic colitis that is associated with the JAK2V617F mutation, which is also known to induce arterial and deep venous thrombosis. Ischaemic colitis is caused by several predisposing conditions, such as embolism, thrombophilia or thrombogenic drug usage. The presence of an …

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    Footnotes

    • Competing interests None.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; internally peer reviewed.