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Stem cell markers characterise familial adenomatous polyposis
  1. Tingting Wang1,
  2. Khay Guan Yeoh1,
  3. Manuel Salto-Tellez1,2
  1. 1Cancer Science Institute Singapore, National University Health System and National University of Singapore, Singapore
  2. 2Centre for Cancer Research and Cell Biology, Queen's University, Belfast, UK
  1. Correspondence to Professor Manuel Salto-Tellez, CCRCB, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK; m.salto-tellez{at}

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We read with great interest the paper by Lewis et al1 on the association between increased expression of stem cell markers, including leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5), Musashi-1, Bmi1 and CD44, and the severity of intestinal polyposis in Apc1322T mice, …

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  • Funding This study was supported by National Medical Research Council, Singapore. Grant Number MH 9503/22.

  • Competing interests None.

  • Ethics approval This study was conducted with the approval of National University of Singapore (NUS1015).

  • Provenance and peer review Not commissioned; internally peer reviewed.