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Fourier analysis of arterial pulse in patients with advanced cirrhosis indicates reduced wave reflections that may protect against manifest cardiac dysfunction
  1. Jens H Henriksen1,
  2. Stefan Fuglsang1,
  3. Flemming Bendtsen2
  1. 1Department of Clinical Physiology
  2. 2Department Gastroenterology, Hvidovre Hospital, University of Copenhagen, Copenhagen Denmark
  1. Correspondence to Professor Jens H Henriksen, Department of Clinical Physiology, Hvidovre Hospital, University of Copenhagen, DK-2650 Hvidovre, Denmark; jens.h.henriksen{at}

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Several recent articles in Gut have dealt with different aspects of the systemic circulation in liver disease.1–4 Patients with advanced cirrhosis have cardiovascular dysfunction and altered mechanics of large and small arteries.5 ,6 The configuration of the arterial pressure curve from these patients may disclose a flatter profile with fewer peaks.7 However, systematic investigations have not been performed. We applied the fast Fourier analysis to quantify the components of the arterial pressure curve …

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  • Competing interests None.

  • Patient consent Obtained.

  • Ethics approval The study was approved by the Ethics Committee for Medical Research in Copenhagen, Denmark.

  • Provenance and peer review Not commissioned; internally peer reviewed.