Table of contents

Original articles

Oesophagus

• Original article: Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells (9 December, 2011)

  DunFa Peng, Abbes Belkhiri, TianLing Hu, Rupesh Chaturvedi, Mohammad Asim, Keith T Wilson, Alexander Zaika, Wael El-Rifai

Stomach

• Original article: A prospective cohort study of obesity and risk of oesophageal and gastric adenocarcinoma in the NIH–AARP Diet and Health Study (15 December, 2011)

  Mark G O'Doherty, Neal D Freedman, Albert R Hollenbeck, Arthur Schatzkin, Christian C Abnet

Intestinal inflammation

• Original article: Induction of dsRNA-activated protein kinase links mitochondrial unfolded protein response to the pathogenesis of intestinal inflammation (13 October, 2011)

  Eva Rath, Emanuel Berger, Anja Messlik, Tiago Nunes, Bo Liu, Sandy C Kim, Nick Hoogenraad, Miquel Sans, R Balfour Sartor, Dirk Haller

Inflammatory bowel disease

• Original article: Increased risk of inflammatory bowel disease in women with endometriosis: a nationwide Danish cohort study (19 December, 2011)

  Tine Jess, Morten Frisch, Kristian Tore Jørgensen, Bo Vestergaard Pedersen, Nete Munk Nielsen

Neurogasteroenterology

• Original article: The brain–gut pathway in functional gastrointestinal disorders is bidirectional: a 12-year prospective population-based study (10 January, 2012)

  N A Koloski, M Jones, J Kalantar, M Weltman, J Zaguirre, N J Talley

Colon

• Original article: Prognostic gene expression signature associated with two molecularly distinct subtypes of colorectal cancer (13 October, 2011)

  Sang Cheul Oh, Yun-Yong Park, Eun Sung Park, Jae Yun Lim, Soo Mi Kim, Sang-Bae Kim, Jongseung Kim, Sang Cheol Kim, In-Sun Chu, J Joshua Smith, R Daniel Beauchamp, Timothy J Yeatman, Scott Kopetz, Ju-Seog Lee
• Original article: Postmenopausal hormone therapy and colorectal cancer risk by molecularly defined subtypes among older women (24 October, 2011)

  David Limsui, Robert A Vierkant, Lori S Tillmans, Alice H Wang, Daniel J Weisenberger, Peter W Laird, Charles F Lynch, Kristin E Anderson, Amy J French, Robert W Haile, Lisa J Harnack, John D Potter, Susan L Slager, Thomas C Smyrk, Stephen N Thibodeau, James R Cerhan, Paul J Limburg
• Original article: β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells (14 November, 2011)

  Helena J M Smartt, Alexander Greenhough, Paloma Ordóñez-Morán, Elena Talero, Catherine A Cherry, Catherine A Wallam, Lee Parry, Manal Al Kharusi, Heather R Roberts, John M Mariadason, Alan R Clarke, Joerg Huelsken, Ann C Williams, Chris Paraskeva

Pancreas

• Original article: Detection of pancreatic cancer tumours and precursor lesions by cathepsin E activity in mouse models (7 November, 2011)

  Zobeida Cruz-Monserrate, Wael R Abd-Elgaliel, Tobias Grote, Defeng Deng, Baoan Ji, Thiruvengadam Arumugam, Huamin Wang, Ching-Hsuan Tung, Craig D Logsdon

Hepatology

• Original article: NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease (17 March, 2012) Free

  Wing-Kin Syn, Kolade M Agboola, Marzena Swiderska, Gregory A Michelotti, Evaggelia Liaskou, Herbert Pang, Guanhua Xie, George Philips, Isaac S Chan, Gamze F Karaca, Thiago de Almeida Pereira, Yuping Chen, Zhiyong Mi, Paul C Kuo, Steve S Choi, Cynthia D Guy, Manal F Abdelmalek, Anna Mae Diehl
• Original article: Hepatic cell-to-cell transmission of small silencing RNA can extend the therapeutic reach of RNA interference (RNAi) (23 December, 2011)

  Qiuwei Pan, Vedashree Ramakrishnaiah, Scot Henry, Suomi Fouraschen, Petra E de Ruiter, Jaap Kwekkeboom, Hugo W Tilanus, Harry L A Janssen, Luc J W van der Laan