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MRI as the new reference standard in quantifying liver steatosis: the need for international guidelines
  1. Dimitri Aristotle Raptis1,
  2. Michael Alexander Fischer2,
  3. Daniel Nanz2,
  4. Rolf Graf1,
  5. Pierre-Alain Clavien1
  1. 1Department of Visceral and Transplant Surgery, Swiss Hepato-Pancreatico-Biliary (HPB) Center, University Hospital Zurich, Zurich, Switzerland
  2. 2Department of Interventional and Diagnostic Radiology, University Hospital Zurich, Zurich, Switzerland
  1. Correspondence to Dr Pierre-Alain Clavien, Department of Surgery, University Hospital of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland; clavien{at}

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We read with great interest the letter to the editor by Guiu and Cercueil1 referring to our study on invasive and non-invasive methods in quantifying liver fat content.2 The authors commented on the MRI T2*-bias associated with presence of iron in the liver. They contend that multi-echo (ME) rather than dual-echo (DE) sequences are superior, and indicate the potential confounding effect of a relatively high flip angle and T1 bias associated with the sequences used in our study. Furthermore, they emphasise the need for international guidelines regarding sequences used by MRI …

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  • Funding The Swiss National Science Foundation has funded PAC and RG by grant no 32003B-109906.

  • Competing interests None.

  • Provenance and peer review Commissioned; externally peer reviewed.