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  • Ischaemia-induced mucus barrier loss and bacterial penetration are rapidly counteracted by increased goblet cell secretory activity in human and rat colon

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Colon
Original article
Ischaemia-induced mucus barrier loss and bacterial penetration are rapidly counteracted by increased goblet cell secretory activity in human and rat colon

Authors

  • Joep Grootjans Department of Surgery, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The NetherlandsDepartment of Internal Medicine, Slotervaartziekenhuis, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Inca H R Hundscheid Department of Surgery, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands PubMed articlesGoogle scholar articles
  • Kaatje Lenaerts Department of Surgery, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands PubMed articlesGoogle scholar articles
  • Bas Boonen Department of Surgery, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands PubMed articlesGoogle scholar articles
  • Ingrid B Renes Laboratory of Paediatrics, Division of Neonatology, Erasmus MC-Sophia, Rotterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Fons K Verheyen Department of Molecular Cell Biology and Electron Microscopy, Centre for Research Innovation, Support and Policy (CRISP), Maastricht University Medical Centre, Maastricht, The Netherlands PubMed articlesGoogle scholar articles
  • Cornelis H Dejong Department of Surgery, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands PubMed articlesGoogle scholar articles
  • Maarten F von Meyenfeldt Department of Surgery, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands PubMed articlesGoogle scholar articles
  • Geerard L Beets Department of Surgery, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands PubMed articlesGoogle scholar articles
  • Wim A Buurman Department of Surgery, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Joep Grootjans, Department of Surgery, Maastricht University Medical Centre, Universiteitssingel 50, Maastricht 6229 ER, The Netherlands; j.grootjans{at}maastrichtuniversity.nl
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Citation

Grootjans J, Hundscheid IHR, Lenaerts K, et al
Ischaemia-induced mucus barrier loss and bacterial penetration are rapidly counteracted by increased goblet cell secretory activity in human and rat colon
Gut 2013;62:250-258.

Publication history

  • Revised March 12, 2012
  • Accepted March 25, 2012
  • First published May 25, 2012.
Online issue publication 
April 18, 2016

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