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In vivo diagnosis of lymphocytic colitis by confocal laser endomicroscopy
  1. Helmut Neumann1,
  2. Martin Grauer1,
  3. Michael Vieth2,
  4. Markus F Neurath1
  1. 1Department of Medicine I, University of Erlangen-Nuremberg, Erlangen, Germany
  2. 2Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany
  1. Correspondence to Professor Helmut Neumann, Professor of Medicine, Department of Medicine I, University of Erlangen-Nuremberg, Ulmenweg 18, 91054 Erlangen, Germany; helmut.neumann{at}

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We read with interest the paper by Moussata et al and the GI snapshot by Neufert et al, published in recent issues of Gut.1 ,2 The authors described in these outstanding articles the potential of confocal laser endomicroscopy (CLE) to either image intramucosal bacteria in vivo in patients with inflammatory bowel diseases and also to visualise disease specific findings (‘foamy macrophages’) in a patient with Mycobacterium avium intracellulare infection.

CLE was recently introduced as a new emerging endoscopic imaging modality which due to its inherent capability of providing in vivo images of microscopic tissue changes at 1000-fold …

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  • Competing interests None.

  • Ethics approval This study was approved by the Ethical Committee of the University of Erlangen-Nuremberg.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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