Table of contents

Original articles

Oesophagus

• Original article: Endoscopic assessment of the oesophageal features of eosinophilic oesophagitis: validation of a novel classification and grading system (22 May, 2012)

  Ikuo Hirano, Nelson Moy, Michael G Heckman, Colleen S Thomas, Nirmala Gonsalves, Sami R Achem

Stomach

• Original article: CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancer (25 April, 2012)

  Shouyu Wang, Xuming Wu, Jianbing Zhang, Yansu Chen, Jin Xu, Xiaowei Xia, Song He, Fulin Qiang, Aiping Li, Yongqian Shu, Oluf Dimitri Røe, Gang Li, Jianwei W Zhou

Coeliac disease

• Original article: Identification of a potential physiological precursor of aberrant cells in refractory coeliac disease type II (3 July, 2012)

  Frederike Schmitz, Jennifer M L Tjon, Yuching Lai, Allan Thompson, Yvonne Kooy-Winkelaar, Richard J L F Lemmers, Hein W Verspaget, M Luisa Mearin, Frank J Staal, Marco W Schreurs, Tom Cupedo, Anton W Langerak, Chris J Mulder, Jeroen van Bergen, Frits Koning

Inflammatory bowel disease

• Original article: Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in mice (22 March, 2012)

  Christian Sina, Simone Lipinski, Olga Gavrilova, Konrad Aden, Ateequr Rehman, Andreas Till, Andrea Rittger, Rainer Podschun, Ulf Meyer-Hoffert, Robert Haesler, Emilie Midtling, Katrin Pütsep, Michael A McGuckin, Stefan Schreiber, Paul Saftig, Philip Rosenstiel
• Original article: Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases (19 September, 2012)

  Henri Duboc, Sylvie Rajca, Dominique Rainteau, David Benarous, Marie-Anne Maubert, Elodie Quervain, Ginette Thomas, Véronique Barbu, Lydie Humbert, Guillaume Despras, Chantal Bridonneau, Fabien Dumetz, Jean-Pierre Grill, Joëlle Masliah, Laurent Beaugerie, Jacques Cosnes, Olivier Chazouillères, Raoul Poupon, Claude Wolf, Jean-Maurice Mallet, Philippe Langella, Germain Trugnan, Harry Sokol, Philippe Seksik

Colon

• Original article:

  A combined oncogenic pathway signature of BRAF, KRAS and PI3KCA mutation improves colorectal cancer classification and cetuximab treatment prediction

  (14 July, 2012)

  Sun Tian, Iris Simon, Victor Moreno, Paul Roepman, Josep Tabernero, Mireille Snel, Laura van't Veer, Ramon Salazar, Rene Bernards, Gabriel Capella
• Original article: Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling (25 April, 2012)

  Astrid De Boeck, Patrick Pauwels, Karen Hensen, Jean-Luc Rummens, Wendy Westbroek, An Hendrix, Dawn Maynard, Hannelore Denys, Kathleen Lambein, Geert Braems, Christian Gespach, Marc Bracke, Olivier De Wever
• Original article: Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice (26 June, 2012)

  Hyun-Seuk Moon, Xiaowen Liu, Jutta M Nagel, John P Chamberland, Kalliope N Diakopoulos, Mary T Brinkoetter, Maria Hatziapostolou, Yan Wu, Simon C Robson, Dimitrios Iliopoulos, Christos S Mantzoros
• Original article: An epigenetic role for PRL-3 as a regulator of H3K9 methylation in colorectal cancer (16 February, 2012)

  Yongxia Liu, Ping Zheng, Yuhong Liu, Tianhai Ji, Xunhua Liu, Su Yao, Xing Cheng, Ying Li, Lin Chen, Zhengquan Xiao, Jun Zhou, Jianming Li

Pancreas

• Original article:

  CFTR, SPINK1, CTRC and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated?

  (17 March, 2012)

  Jonas Rosendahl, Olfert Landt, Jana Bernadova, Peter Kovacs, Niels Teich, Hans Bödeker, Volker Keim, Claudia Ruffert, Joachim Mössner, Andreas Kage, Michael Stumvoll, David Groneberg, Renate Krüger, Werner Luck, Matthias Treiber, Michael Becker, Heiko Witt

Hepatology

• Original article: A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity (7 July, 2012)

  Iulia Oancea, Chin Wen Png, Indrajit Das, Rohan Lourie, Ingrid G Winkler, Rajaraman Eri, Nathan Subramaniam, H A Jinnah, Brett C McWhinney, Jean-Pierre Levesque, Michael A McGuckin, John A Duley, Timothy H J Florin
• Original article: Metformin decreases hepatocellular carcinoma risk in a dose-dependent manner: population-based and in vitro studies (7 July, 2012)

  Hsiao-Ping Chen, Jeng-Jer Shieh, Chia-Che Chang, Tzu-Ting Chen, Jaw-Town Lin, Ming-Shiang Wu, Jeng-Horng Lin, Chun-Ying Wu