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Original article
Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice
  1. Hyun-Seuk Moon1,
  2. Xiaowen Liu1,
  3. Jutta M Nagel1,
  4. John P Chamberland1,
  5. Kalliope N Diakopoulos1,
  6. Mary T Brinkoetter1,
  7. Maria Hatziapostolou2,3,
  8. Yan Wu4,
  9. Simon C Robson4,
  10. Dimitrios Iliopoulos2,3,
  11. Christos S Mantzoros1,5
  1. 1Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
  2. 2Department of Cancer Immunology & AIDS, Dana-Farber Cancer Institute, Boston, Massachusetts, USA
  3. 3Department of Microbiology & Immunobiology, Harvard Medical School, Boston, Massachusetts, USA
  4. 4Department of Medicine, Gastroenterology and Transplantation Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
  5. 5Section of Endocrinology, Boston VA Healthcare System, Harvard Medical School, Boston, Massachusetts, USA
  1. Correspondence to Dr Christos S Mantzoros, Professor of Medicine, Harvard Medical School, JP9B52A, 150 S. Huntington Ave, Boston, MA 02130, USA; cmantzor{at}bidmc.harvard.edu

Footnotes

  • H-SM, XL, JMN and JPC contributed equally to this work.

  • Funding This study was supported by a joint California Walnut Commission and AICR grant. The Mantzoros Laboratory is supported by DK79929-02, DK058785-08 and DK081913-02 grants from the National Institute of Diabetes and Digestive and Kidney Diseases. The Robson laboratory acknowledges support from NIH via HL076540 and HL094400. The Mantzoros Laboratory is also supported by a discretionary grant from Beth Israel Deaconess Medical Center and a VA Merit award (grant 10684957).

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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Footnotes

  • H-SM, XL, JMN and JPC contributed equally to this work.

  • Funding This study was supported by a joint California Walnut Commission and AICR grant. The Mantzoros Laboratory is supported by DK79929-02, DK058785-08 and DK081913-02 grants from the National Institute of Diabetes and Digestive and Kidney Diseases. The Robson laboratory acknowledges support from NIH via HL076540 and HL094400. The Mantzoros Laboratory is also supported by a discretionary grant from Beth Israel Deaconess Medical Center and a VA Merit award (grant 10684957).

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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