A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise

Wataru Aoi; Yuji Naito; Tomohisa Takagi; Yuko Tanimura; Yoshikazu Takanami; Yukari Kawai; Kunihiro Sakuma; Liu Po Hang; Katsura Mizushima; Yasuko Hirai; Ryota Koyama; Sayori Wada; Akane Higashi; Satoshi Kokura; Hiroshi Ichikawa; Toshikazu Yoshikawa

doi:10.1136/gutjnl-2011-300776

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A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise

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Wataru Aoi Laboratory of Health Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto, Japan PubMed articles Google scholar articles
Yuji Naito Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan PubMed articles Google scholar articles
Tomohisa Takagi Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan PubMed articles Google scholar articles
Yuko Tanimura Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan PubMed articles Google scholar articles
Yoshikazu Takanami Department of Home Economics, Otsuma Women's University, Tokyo, Japan PubMed articles Google scholar articles
Yukari Kawai Louis Pasteur Center for Medical Research, Kyoto, Japan PubMed articles Google scholar articles
Kunihiro Sakuma Health Science Center, Toyohashi University of Technology, Toyohashi, Japan PubMed articles Google scholar articles
Liu Po Hang Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan PubMed articles Google scholar articles
Katsura Mizushima Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan PubMed articles Google scholar articles
Yasuko Hirai Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan PubMed articles Google scholar articles
Ryota Koyama Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan PubMed articles Google scholar articles
Sayori Wada Laboratory of Health Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto, Japan PubMed articles Google scholar articles
Akane Higashi Laboratory of Health Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto, Japan PubMed articles Google scholar articles
Satoshi Kokura Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan PubMed articles Google scholar articles
Hiroshi Ichikawa Department of Medical Life Systems, Doshisha University, Kyotanabe, Japan PubMed articles Google scholar articles
Toshikazu Yoshikawa Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan PubMed articles Google scholar articles

Correspondence to Dr Wataru Aoi, Laboratory of Health Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, 1-5 Hangi-cho Shimogamo, Sakyo-ku, Kyoto 606-8522, Japan; waoi{at}koto.kpu-m.ac.jp

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Citation

Aoi W, Naito Y, Takagi T, et al

A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise

Gut 2013;62:882-889.

Publication history

Revised June 16, 2012
Accepted July 3, 2012
First published July 31, 2012.

Online issue publication

March 01, 2018

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