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The impact of Crohn's disease genes on healthy human gut microbiota: a pilot study

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  • CQ and EL contributed equally

  • Contributors MDA had the original idea, and designed the study together with LA and LE; ANA, NJT and LA collected and characterised the study subjects and acquired data; EL, ANA and LE performed sequencing of microbiota; MDA supervised genotyping; CQ, EL, ANA, AFA, JR and DG carried out statistical analyses; data analysis and interpretation was done by CQ and MDA, who drafted the manuscript with critical revision for important intellectual content from all other coauthors.

  • Funding Supported by funds from the Swedish Research Council (VR) to MDA and AFA, the Swedish Society of Medicine to LA, the EU project TORNADO to LE and JR and the Söderbergs Foundation to LE. CQ is funded through an EPSRC Career Acceleration Fellowship EP/H003851/1.

  • Competing interests None.

  • Ethics approval Karolinska Institutet, Stockholm, Sweden.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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