Table of contents

Original articles

Upper GI cancer

• Original article: Hospital volume, proportion resected and mortality from oesophageal and gastric cancer: a population-based study in England, 2004–2008 (19 October, 2012)

  Victoria H Coupland, Jesper Lagergren, Margreet Lüchtenborg, Ruth H Jack, William Allum, Lars Holmberg, George B Hanna, Neil Pearce, Henrik Møller

Inflammatory bowel disease

• Original article: Transcriptional analysis of the intestinal mucosa of patients with ulcerative colitis in remission reveals lasting epithelial cell alterations (7 November, 2012) Free

  Núria Planell, Juan J Lozano, Rut Mora-Buch, M Carme Masamunt, Mireya Jimeno, Ingrid Ordás, Miriam Esteller, Elena Ricart, Josep M Piqué, Julián Panés, Azucena Salas
• Original article: Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes (28 April, 2012)

  Katja Christodoulou, Anthony E Wiskin, Jane Gibson, William Tapper, Claire Willis, Nadeem A Afzal, Rosanna Upstill-Goddard, John W Holloway, Michael A Simpson, R Mark Beattie, Andrew Collins, Sarah Ennis

Neurogastroenterology

• Original article: Identifying and testing candidate genetic polymorphisms in the irritable bowel syndrome (IBS): association with TNFSF15 and TNFα (8 June, 2012)

  Caroline Swan, Nathalie P Duroudier, Eugene Campbell, Abed Zaitoun, Margaret Hastings, George E Dukes, Joanne Cox, Fiona M Kelly, Jonathan Wilde, Mark G Lennon, Keith R Neal, Peter J Whorwell, Ian P Hall, Robin C Spiller

Coeliac disease

• Original article: Kinetics of the histological, serological and symptomatic responses to gluten challenge in adults with coeliac disease (22 May, 2012)

  Daniel Leffler, Detlef Schuppan, Kumar Pallav, Robert Najarian, Jeffery D Goldsmith, Joshua Hansen, Toufic Kabbani, Melinda Dennis, Ciarán P Kelly

Colon

• Original article: Risk adjusted benchmarking of abdominoperineal excision for rectal adenocarcinoma in the context of the Belgian PROCARE improvement project (23 April, 2012)

  Freddy Penninckx, Steffen Fieuws, Koen Beirens, Pieter Demetter, Wim Ceelen, Alex Kartheuser, Gaetan Molle, Jean Van de Stadt, Koen Vindevoghel, Elizabeth Van Eycken, on behalf of PROCARE
• Original article: In situ validation of an intestinal stem cell signature in colorectal cancer (25 May, 2012)

  Jennifer L Ziskin, Debra Dunlap, Murat Yaylaoglu, Imola K Fodor, William F Forrest, Rajesh Patel, Nianfeng Ge, Gordon G Hutchins, James K Pine, Philip Quirke, Hartmut Koeppen, Adrian M Jubb

Pancreas

• Original article:

  Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts

  (2 August, 2012)

  Mitsuro Kanda, Spencer Knight, Mark Topazian, Sapna Syngal, James Farrell, Jeffrey Lee, Ihab Kamel, Anne Marie Lennon, Michael Borges, Angela Young, Sho Fujiwara, Junro Seike, James Eshleman, Ralph H Hruban, Marcia Irene Canto, Michael Goggins
• Original article: Claudin-4-targeted optical imaging detects pancreatic cancer and its precursor lesions (7 June, 2012)

  Albrecht Neesse, Anke Hahnenkamp, Heidi Griesmann, Malte Buchholz, Stefan A Hahn, Abdelouahid Maghnouj, Volker Fendrich, Janine Ring, Bence Sipos, David A Tuveson, Christoph Bremer, Thomas M Gress, Patrick Michl

Hepatology

• Original article:

  Estrogen-related receptor γ controls hepatic CB₁ receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol

  (29 September, 2012)

  Don-Kyu Kim, Yong-Hoon Kim, Hyun-Hee Jang, Jinyoung Park, Jung Ran Kim, Minseob Koh, Won-Il Jeong, Seung-Hoi Koo, Tae-Sik Park, Chul-Ho Yun, Seung Bum Park, John Y L Chiang, Chul-Ho Lee, Hueng-Sik Choi
• Original article: Combination therapies with NS5A, NS3 and NS5B inhibitors on different genotypes of hepatitis C virus in human hepatocyte chimeric mice (15 January, 2013)

  Niu Shi, Nobuhiko Hiraga, Michio Imamura, C Nelson Hayes, Yizhou Zhang, Keiichi Kosaka, Akihito Okazaki, Eisuke Murakami, Masataka Tsuge, Hiromi Abe, Hiroshi Aikata, Shoichi Takahashi, Hidenori Ochi, Chise Tateno-Mukaidani, Katsutoshi Yoshizato, Hirotaka Matsui, Akinori Kanai, Toshiya Inaba, Fiona McPhee, Min Gao, Kazuaki Chayama