A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis

Paul J Rutgeerts; Richard N Fedorak; Daan W Hommes; Andreas Sturm; Daniel C Baumgart; Brian Bressler; Stefan Schreiber; John C Mansfield; Marna Williams; Meina Tang; Jennifer Visich; Xiaohui Wei; Mary Keir; Diana Luca; Dimitri Danilenko; Jackson Egen; Sharon O'Byrne

doi:10.1136/gutjnl-2011-301769

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Inflammatory bowel disease

Original article

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis

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	Abstract	Full	Pdf
Jun 2012	267	76	84
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Aug 2012	115	113	66
Sep 2012	99	88	53
Oct 2012	69	71	56
Nov 2012	93	67	40
Dec 2012	85	53	45
Jan 2013	115	91	55
Feb 2013	109	68	43
Mar 2013	103	84	43
Apr 2013	112	91	46
May 2013	100	66	54
Jun 2013	71	55	36
Jul 2013	2843	192	315
Aug 2013	1364	84	121
Sep 2013	855	468	202
Oct 2013	675	176	73
Nov 2013	491	140	80
Dec 2013	341	133	68
Jan 2014	192	122	60
Feb 2014	77	328	118
Mar 2014	80	128	37
Apr 2014	82	130	49
May 2014	101	204	74
Jun 2014	61	128	69
Jul 2014	75	90	47
Aug 2014	65	69	50
Sep 2014	63	71	42
Oct 2014	58	83	42
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Jan 2015	50	65	44
Feb 2015	39	50	33
Mar 2015	37	77	55
Apr 2015	40	64	40
May 2015	52	100	47
Jun 2015	56	61	43
Jul 2015	36	99	43
Aug 2015	23	75	45
Sep 2015	44	61	40
Oct 2015	18	53	25
Nov 2015	42	58	39
Dec 2015	35	63	41
Jan 2016	40	54	47
Feb 2016	36	60	24
Mar 2016	35	39	37
Apr 2016	39	59	35
May 2016	26	49	36
Jun 2016	38	53	32
Jul 2016	35	47	54
Aug 2016	44	41	53
Sep 2016	57	55	41
Oct 2016	54	64	51
Nov 2016	53	33	32
Dec 2016	31	26	21
Jan 2017	43	26	29
Feb 2017	16	30	32
Mar 2017	7	34	28
Apr 2017	13	59	19
May 2017	13	60	29
Jun 2017	29	49	17
Jul 2017	260	257	26
Aug 2017	258	250	22
Sep 2017	125	91	23
Oct 2017	70	54	16
Nov 2017	78	60	20
Dec 2017	64	48	24
Jan 2018	90	70	19
Feb 2018	54	37	30
Mar 2018	65	49	19
Apr 2018	62	54	22
May 2018	62	61	17
Jun 2018	59	44	19
Jul 2018	67	63	23
Aug 2018	37	29	14
Sep 2018	44	34	12
Oct 2018	48	40	23
Nov 2018	58	34	20
Dec 2018	55	40	22
Jan 2019	61	43	23
Feb 2019	33	30	23
Mar 2019	46	43	25
Apr 2019	41	37	34
May 2019	45	39	30
Jun 2019	29	27	35
Jul 2019	38	28	30
Aug 2019	43	33	36
Sep 2019	52	41	25
Oct 2019	37	18	33
Nov 2019	47	41	12
Dec 2019	61	51	30
Jan 2020	69	60	36
Feb 2020	33	23	19
Mar 2020	40	34	24
Apr 2020	36	28	25
May 2020	34	24	14
Jun 2020	32	23	30
Jul 2020	32	28	16
Aug 2020	42	36	19
Sep 2020	68	56	20
Oct 2020	56	44	19
Nov 2020	47	37	14
Dec 2020	62	49	25
Jan 2021	55	44	37
Feb 2021	39	35	33
Mar 2021	72	60	42
Apr 2021	65	43	33
May 2021	45	45	31
Jun 2021	29	27	18
Jul 2021	38	38	28
Aug 2021	62	61	41
Sep 2021	58	58	48
Oct 2021	54	50	25
Nov 2021	73	65	36
Dec 2021	94	79	28
Jan 2022	79	65	34
Feb 2022	89	91	25
Mar 2022	110	107	21
Apr 2022	116	111	41
May 2022	78	75	36
Jun 2022	72	67	16
Jul 2022	82	81	12
Aug 2022	68	64	25
Sep 2022	88	82	41
Oct 2022	117	113	33
Nov 2022	65	53	17
Dec 2022	58	49	9
Jan 2023	92	76	31
Feb 2023	75	70	25
Mar 2023	65	59	22
Apr 2023	69	54	56
May 2023	38	28	22
Jun 2023	45	43	11
Jul 2023	32	27	18
Aug 2023	53	47	38
Sep 2023	54	51	34
Oct 2023	64	60	18
Nov 2023	100	89	13
Dec 2023	144	127	14
Jan 2024	40	36	22
Feb 2024	43	39	10
Mar 2024	54	51	50
Total	15441	10001	5404

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