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PTU-077 Diagnostic Potential of Volatile Organic Compounds as Urine Biomarkers in Inflammatory Bowel Disease
  1. H Jayasena1,
  2. T Khalid2,
  3. C S Probert2
  1. 1Gastroenterology, Bristol Royal Infirmary, Bristol
  2. 2University of Liverpool, Liverpool, UK


Introduction The potential of urinary VOCs as biomarkers in IBD is unknown.

Methods Patients recruited from outpatient clinic, with proven Crohn’s disease (CDN = 35) and ulcerative colitis (UC N = 49), IBS (N = 22) and 41 healthy volunteers. Concurrent disease activity was recorded using Harvey-Bradshaw index (HBI) in CD and simple clinical colitis activity index (SCCAI) in UC. Urine headspace gas was sampled using SPME and was transferred to GCMS for VOC identification.

Abstract PTU-077 Table

Conclusion Urine VOCs are capable of distinguishing IBD from IBS.

Disclosure of Interest None Declared

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