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Authors’ response: Observations suggesting bioactive Fgf15 is not present in mouse blood
  1. Matias A Avila
  1. Correspondence to Dr Matias A Avila, Division of Hepatology and Gene Therapy, CIMA, Universidad de Navarra, Pamplona 31008, Spain; maavila{at}

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We have read with interest Dr Mats Rudling's letter regarding our recent article on the role of Fgf15 in liver regeneration and the liver growth-promoting effects of bile acids.1 Our work was based on the use of Fgf15 knockout mice, and in these mice we indeed found impaired liver regeneration and bile acid metabolism after partial hepatectomy and reduced liver cell proliferation upon bile acid feeding.2 The fact that FGFR4 deficient mice …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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