Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration

Markus Tschurtschenthaler; Jun Wang; Cornelia Fricke; Teresa M J Fritz; Lukas Niederreiter; Timon E Adolph; Edina Sarcevic; Sven Künzel; Felix A Offner; Ulrich Kalinke; John F Baines; Herbert Tilg; Arthur Kaser

doi:10.1136/gutjnl-2013-305863

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Gut microbiota

Original article

Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration

Authors

Markus Tschurtschenthaler Division of Gastroenterology & Hepatology, Department of Medicine, University of Cambridge, Cambridge, UK Department of Medicine I, Innsbruck Medical University, Innsbruck, Austria PubMed articles Google scholar articles
Jun Wang Max Planck Institute for Evolutionary Biology, Plön, Germany Institute for Experimental Medicine, Christian-Albrechts-University of Kiel, Kiel, Germany PubMed articles Google scholar articles
Cornelia Fricke Department of Medicine II, Innsbruck Medical University, Innsbruck, Austria PubMed articles Google scholar articles
Teresa M J Fritz Department of Medicine II, Innsbruck Medical University, Innsbruck, Austria PubMed articles Google scholar articles
Lukas Niederreiter Division of Gastroenterology & Hepatology, Department of Medicine, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Timon E Adolph Division of Gastroenterology & Hepatology, Department of Medicine, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Edina Sarcevic Department of Pathology, Academic Teaching Hospital Feldkirch, Feldkirch, Austria PubMed articles Google scholar articles
Sven Künzel Max Planck Institute for Evolutionary Biology, Plön, Germany PubMed articles Google scholar articles
Felix A Offner Department of Pathology, Academic Teaching Hospital Feldkirch, Feldkirch, Austria PubMed articles Google scholar articles
Ulrich Kalinke Division of Immunology, Paul-Ehrlich-Institute, Langen, Germany PubMed articles Google scholar articles
John F Baines Max Planck Institute for Evolutionary Biology, Plön, Germany Institute for Experimental Medicine, Christian-Albrechts-University of Kiel, Kiel, Germany PubMed articles Google scholar articles
Herbert Tilg Department of Medicine I, Innsbruck Medical University, Innsbruck, Austria Christian-Doppler Research Laboratory for Gut Inflammation, Innsbruck Medical University, Innsbruck, Austria PubMed articles Google scholar articles
Arthur Kaser Division of Gastroenterology & Hepatology, Department of Medicine, University of Cambridge, Cambridge, UK Department of Medicine II, Innsbruck Medical University, Innsbruck, Austria PubMed articles Google scholar articles

Correspondence to Professor Arthur Kaser, Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Level 5, Box 157, Cambridge CB2 0QQ, UK; ak729{at}cam.ac.uk

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Citation

Tschurtschenthaler M, Wang J, Fricke C, et al

Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration

Gut 2014;63:1921-1931.

Publication history

Received August 13, 2013
Revised January 16, 2014
Accepted January 28, 2014
First published February 20, 2014.

Online issue publication

October 26, 2017

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