Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis

Malin E V Johansson; Jenny K Gustafsson; Jessica Holmén-Larsson; Karolina S Jabbar; Lijun Xia; Hua Xu; Fayez K Ghishan; Frederic A Carvalho; Andrew T Gewirtz; Henrik Sjövall; Gunnar C Hansson

doi:10.1136/gutjnl-2012-303207

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Inflammatory bowel disease

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Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis

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May 2016	64	135	49
Jun 2016	60	135	76
Jul 2016	75	94	38
Aug 2016	66	98	45
Sep 2016	69	120	60
Oct 2016	87	253	60
Nov 2016	53	84	57
Dec 2016	76	71	50
Jan 2017	108	105	61
Feb 2017	84	65	39
Mar 2017	27	98	57
Apr 2017	32	142	66
May 2017	23	169	49
Jun 2017	62	86	37
Jul 2017	127	106	52
Aug 2017	173	123	35
Sep 2017	189	117	58
Oct 2017	181	133	40
Nov 2017	158	110	46
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Jan 2018	193	141	47
Feb 2018	202	129	42
Mar 2018	235	144	63
Apr 2018	186	137	49
May 2018	187	149	61
Jun 2018	159	123	32
Jul 2018	196	143	47
Aug 2018	196	152	44
Sep 2018	156	122	46
Oct 2018	253	143	65
Nov 2018	247	139	65
Dec 2018	173	129	40
Jan 2019	198	168	73
Feb 2019	192	146	53
Mar 2019	203	141	81
Apr 2019	201	133	74
May 2019	160	108	67
Jun 2019	150	117	63
Jul 2019	155	109	60
Aug 2019	163	140	65
Sep 2019	151	114	70
Oct 2019	169	123	56
Nov 2019	125	103	48
Dec 2019	160	113	35
Jan 2020	160	114	79
Feb 2020	146	100	54
Mar 2020	227	201	58
Apr 2020	147	121	63
May 2020	154	128	72
Jun 2020	189	157	120
Jul 2020	147	91	79
Aug 2020	121	101	79
Sep 2020	205	152	109
Oct 2020	166	124	123
Nov 2020	140	116	78
Dec 2020	128	112	63
Jan 2021	166	127	87
Feb 2021	143	91	67
Mar 2021	196	150	92
Apr 2021	168	130	80
May 2021	264	249	69
Jun 2021	428	426	68
Total	18942	14902	11247

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