Dysregulation of interferon regulatory factors impairs the expression of immunostimulatory molecules in hepatitis C virus genotype 1-infected hepatocytes

Esther Larrea; Jose-I Riezu-Boj; Rafael Aldabe; Laura Guembe; Itziar Echeverria; Anangi Balasiddaiah; Pablo Gastaminza; María Pilar Civeira; Pablo Sarobe; Jesus Prieto

doi:10.1136/gutjnl-2012-304377

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Hepatology

Original article

Dysregulation of interferon regulatory factors impairs the expression of immunostimulatory molecules in hepatitis C virus genotype 1-infected hepatocytes

Authors

Esther Larrea Division of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), Pamplona, Spain PubMed articles Google scholar articles
Jose-I Riezu-Boj Division of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), Pamplona, Spain PubMed articles Google scholar articles
Rafael Aldabe Division of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), Pamplona, Spain PubMed articles Google scholar articles
Laura Guembe Department of Morphology, Center for Applied Medical Research (CIMA), Pamplona, Spain PubMed articles Google scholar articles
Itziar Echeverria Division of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), Pamplona, Spain PubMed articles Google scholar articles
Anangi Balasiddaiah Division of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), Pamplona, Spain PubMed articles Google scholar articles
Pablo Gastaminza Department of Cell and Molecular Biology, Centro Nacional de Biotecnologia-CSIC, Madrid, Spain PubMed articles Google scholar articles
María Pilar Civeira University Clinic of Navarra, University of Navarra, Pamplona, Spain CIBERehd, University of Navarra, Pamplona, Spain PubMed articles Google scholar articles
Pablo Sarobe Division of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), Pamplona, Spain PubMed articles Google scholar articles
Jesus Prieto Division of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), Pamplona, Spain University Clinic of Navarra, University of Navarra, Pamplona, Spain CIBERehd, University of Navarra, Pamplona, Spain PubMed articles Google scholar articles

Correspondence to Professor Jesus Prieto or Dr Esther Larrea, Department of Gene Therapy and Hepatology Area, Center for Applied Medical Research, University Clinic of Navarra, University of Navarra, Avda Pio XII 55, Pamplona 31008, Spain; jprieto{at}unav.es or elarrea{at}unav.es

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Citation

Larrea E, Riezu-Boj J, Aldabe R, et al

Dysregulation of interferon regulatory factors impairs the expression of immunostimulatory molecules in hepatitis C virus genotype 1-infected hepatocytes

Gut 2014;63:665-673.

Publication history

Received December 19, 2012
Revised May 30, 2013
Accepted May 31, 2013
First published June 20, 2013.

Online issue publication

February 27, 2014

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