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Author note Gene symbols: CFTR, cystic fibrosis transmembrane conductance regulator; CTRC, chymotrypsinogen C; PRSS1, serine protease 1 (human cationic trypsinogen); SPINK1, serine protease inhibitor Kazal type 1 (pancreatic secretory trypsin inhibitor).
Contributors SB and MS-T designed and executed the study and wrote the manuscript.
Funding These studies were supported by NIH grants R01DK082412, R01DK058088 and R01DK095753 to MS-T.
Competing interests None.
Provenance and peer review Not commissioned; internally peer reviewed.
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