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Letter
Reduced white matter microstructural integrity correlates with cognitive deficits in minimal hepatic encephalopathy

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Footnotes

  • Contributors CM: study concept and design, obtaining funding, performing psychometric tests, analysis and interpretation of data, revising the manuscript. AU and CG-G: performing psychometric tests and biochemical determinations. CA, CF and JG-P: performing TBSS analysis of data, interpretation of data, critical revision of the manuscript. AW, MAS, RG-D and OG: selection of patients, providing the analytical data. RA and VB: magnetic resonance acquisition. VF: study concept and design, obtaining funding, analysis and interpretation of data and writing the article.

  • Funding Supported by grants from Ministerio de Ciencia e Innovación (SAF2011-23051, CSD2008-00005 to VF and FIS PI12/00884 to CM and PSI2010-20168, P1-1B2011-09 to CA), from Consellería de Educación de la Generalitat Valenciana (PROMETEO-2009-027; ACOMP/2012/066, ACOMP/2013/101 to VF and ACOMP/2012/056 to CM and Fundación ERESA (CM).

  • Competing interests None.

  • Ethics approval Comite Etico Hospital Cilinico de Valencia.

  • Provenance and peer review Not commissioned; internally peer reviewed.