Individualised therapy is more cost-effective than dose intensification in patients with Crohn’s disease who lose response to anti-TNF treatment: a randomised, controlled trial

Casper Steenholdt; Jørn Brynskov; Ole Østergaard Thomsen; Lars Kristian Munck; Jan Fallingborg; Lisbet Ambrosius Christensen; Gitte Pedersen; Jens Kjeldsen; Bent Ascanius Jacobsen; Anne Sophie Oxholm; Jakob Kjellberg; Klaus Bendtzen; Mark Andrew Ainsworth

doi:10.1136/gutjnl-2013-305279

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Inflammatory bowel disease

Original article

Individualised therapy is more cost-effective than dose intensification in patients with Crohn’s disease who lose response to anti-TNF treatment: a randomised, controlled trial

Authors

Casper Steenholdt Department of Gastroenterology, Herlev Hospital, Herlev, Denmark PubMed articles Google scholar articles
Jørn Brynskov Department of Gastroenterology, Herlev Hospital, Herlev, Denmark PubMed articles Google scholar articles
Ole Østergaard Thomsen Department of Gastroenterology, Herlev Hospital, Herlev, Denmark PubMed articles Google scholar articles
Lars Kristian Munck Department of Medical Gastroenterology, Køge Hospital, Køge, Denmark PubMed articles Google scholar articles
Jan Fallingborg Department of Medical Gastroenterology, Aalborg Hospital, Aalborg, Denmark PubMed articles Google scholar articles
Lisbet Ambrosius Christensen Department of Hepatology and Gastroenterology V, Aarhus Hospital, Aarhus, Denmark PubMed articles Google scholar articles
Gitte Pedersen Department of Gastroenterology, Hvidovre Hospital, Hvidovre, Denmark PubMed articles Google scholar articles
Jens Kjeldsen Department of Medical Gastroenterology S, Odense Hospital, Odense, Denmark PubMed articles Google scholar articles
Bent Ascanius Jacobsen Department of Medical Gastroenterology, Aalborg Hospital, Aalborg, Denmark PubMed articles Google scholar articles
Anne Sophie Oxholm KORA, Danish Institute for Local and Regional Government Research, Copenhagen, Denmark PubMed articles Google scholar articles
Jakob Kjellberg KORA, Danish Institute for Local and Regional Government Research, Copenhagen, Denmark PubMed articles Google scholar articles
Klaus Bendtzen Institute for Inflammation Research, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark PubMed articles Google scholar articles
Mark Andrew Ainsworth Department of Gastroenterology, Herlev Hospital, Herlev, Denmark PubMed articles Google scholar articles

Correspondence to Casper Steenholdt, Department of Gastroenterology, Herlev Hospital, Herlev Ringvej 75, DK-2730 Herlev, Denmark; steenholdt{at}brygge.dk

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Citation

Steenholdt C, Brynskov J, Thomsen OØ, et al

Individualised therapy is more cost-effective than dose intensification in patients with Crohn’s disease who lose response to anti-TNF treatment: a randomised, controlled trial

Gut 2014;63:919-927.

Publication history

Received May 14, 2013
Revised July 3, 2013
Accepted July 4, 2013
First published July 22, 2013.

Online issue publication

May 05, 2014

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