Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells

Anggakusuma; Che C Colpitts; Luis M Schang; Heni Rachmawati; Anne Frentzen; Stephanie Pfaender; Patrick Behrendt; Richard J P Brown; Dorothea Bankwitz; Joerg Steinmann; Michael Ott; Philip Meuleman; Charles M Rice; Alexander Ploss; Thomas Pietschmann; Eike Steinmann

doi:10.1136/gutjnl-2012-304299

Article info

Hepatology

Original article

Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells

Authors

Anggakusuma Institute of Experimental Virology, Twincore Centre for Experimental and Clinical Infection Research, Hannover, Germany PubMed articles Google scholar articles
Che C Colpitts Departments of Biochemistry and Medical Microbiology and Immunology, Li Ka Shing Insitute of Virology, University of Alberta, Edmonton, Alberta, Canada PubMed articles Google scholar articles
Luis M Schang Departments of Biochemistry and Medical Microbiology and Immunology, Li Ka Shing Insitute of Virology, University of Alberta, Edmonton, Alberta, Canada PubMed articles Google scholar articles
Heni Rachmawati School of Pharmacy, Institut Teknologi Bandung, Bandung, Indonesia PubMed articles Google scholar articles
Anne Frentzen Institute of Experimental Virology, Twincore Centre for Experimental and Clinical Infection Research, Hannover, Germany PubMed articles Google scholar articles
Stephanie Pfaender Institute of Experimental Virology, Twincore Centre for Experimental and Clinical Infection Research, Hannover, Germany PubMed articles Google scholar articles
Patrick Behrendt Institute of Experimental Virology, Twincore Centre for Experimental and Clinical Infection Research, Hannover, Germany Department of Gastroenterology, Hepatology and Endocrinology, Medical School Hannover, Hannover, Germany PubMed articles Google scholar articles
Richard J P Brown Institute of Experimental Virology, Twincore Centre for Experimental and Clinical Infection Research, Hannover, Germany PubMed articles Google scholar articles
Dorothea Bankwitz Institute of Experimental Virology, Twincore Centre for Experimental and Clinical Infection Research, Hannover, Germany PubMed articles Google scholar articles
Joerg Steinmann Institute of Medical Microbiology, University Hospital Essen, Essen, Germany PubMed articles Google scholar articles
Michael Ott Department of Gastroenterology, Hepatology and Endocrinology, Medical School Hannover, Hannover, Germany Translational Research Group, Twincore Centre for Experimental and Clinical Infection Research, Hannover, Germany PubMed articles Google scholar articles
Philip Meuleman Center for Vaccinology, Ghent University, Ghent University hospital, Ghent, Belgium PubMed articles Google scholar articles
Charles M Rice Laboratory of Virology and Infectious Diseases, Center for the Study of Hepatitis C, The Rockefeller University, New York, New York, USA PubMed articles Google scholar articles
Alexander Ploss Laboratory of Virology and Infectious Diseases, Center for the Study of Hepatitis C, The Rockefeller University, New York, New York, USA Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA PubMed articles Google scholar articles
Thomas Pietschmann Institute of Experimental Virology, Twincore Centre for Experimental and Clinical Infection Research, Hannover, Germany PubMed articles Google scholar articles
Eike Steinmann Institute of Experimental Virology, Twincore Centre for Experimental and Clinical Infection Research, Hannover, Germany PubMed articles Google scholar articles

Correspondence to Dr Eike Steinmann, Institute of Experimental Virology, Twincore Center for Experimental and Clinical Infection Research (a joint venture between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI)), Feodor-Lynen-Straße 7-9, Hannover 30625, Germany; eike.steinmann{at}twincore.de

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Citation

Anggakusuma, Colpitts CC, Schang LM, et al

Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells

Gut 2014;63:1137-1149.

Publication history

Received December 10, 2012
Revised July 11, 2013
Accepted July 11, 2013
First published July 31, 2013.

Online issue publication

June 06, 2014

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