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PTU-112 Associations Between Healthcare Resource Utilisation And Health-related Quality Of Life In Cirrhosis
  1. J Orr1,
  2. T Homer2,
  3. L Ternent2,
  4. L Vale2,
  5. M Hudson1,
  6. D Jones1
  1. 1Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, UK
  2. 2Institute of Health and Society, Newcastle University, Newcastle Upon Tyne, UK


Introduction Cirrhosis is associated with impaired Health-Related Quality of Life (HRQoL) and considerable resource use. The association between healthcare utilisation and HRQoL in cirrhosis has not been previously studied.

Methods Four HRQoL tools (SF-36v2, CLDQ, PBC-40 and PROMIS-HAQ) and a healthcare utilisation tool were completed by patients with cirrhosis. Associations between resource utilisation and HRQoL were explored; means were compared using unpaired t tests.

Results 108 patients have been recruited to the study to date with completed tools received from 73. Regular care was required by 29 (40%) with 15 (21%) requiring help with personal care, 12 (16%) with medical care, 18 (25%) with meal preparation and 21 (29%) with housework. All types of care were associated with significantly impaired HRQoL across all domains of all measures tested (p < 0.05). The total number of healthcare consultations (hospital consultations + GP consultations + nurse consultations) was also related to HRQoL with patients who had five or more consultations in a 2 month period showing significant impairment compared to patients with fewer than five consultations. Specifically there was evidence of poorer physical HRQoL with mean SF-36 Physical Component Summary (PCS): 32.5 ± 9.0 vs 40.6 ± 10.6, p = 0.001 and functional restriction evidenced by PROMIS-HAQ: 42.2 ± 26.9 vs 21.1 ± 25.2, p = 0.001. In addition, patients with more consultations had poorer social HRQoL with SF-36 Social Functioning (SF): 31.3 ± 12.3 vs 40.2 ± 12.8, p = 0.005 and PBC-40 social: 36.3 ± 9.9 vs 30.0 ± 9.7 p = 0.01.

Conclusion The need for any type of regular care and more frequent consultations with healthcare professionals are associated with poorer HRQoL in cirrhosis.

Disclosure of Interest None Declared.

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