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Hepatitis B virus seromarkers clearance and risk of hepatocellular carcinoma: serious risks of misinterpretation
  1. Alexandre Pariente
  1. Correspondence to Dr Alexandre Pariente, Unité d'hépatogastroentérologie, Centre Hospitalier, Boulevard Hauterive, Pau 64000, France; alex.pariente{at}

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Liu et al 1 have to be commended for their recent report concerning the predictive value of hepatitis B virus (HBV) seromarkers clearance for hepatocellular carcinoma (HCC) risk in the REVEAL study. There are, however, some limits and interrogations:

  • The incidence rates of HCC are measured from baseline (as the characteristics of the patients) and not from …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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