The relationship between infliximab concentrations, antibodies to infliximab and disease activity in Crohn's disease

Niels Vande Casteele; Reena Khanna; Barrett G Levesque; Larry Stitt; G Y Zou; Sharat Singh; Steve Lockton; Scott Hauenstein; Linda Ohrmund; Gordon R Greenberg; Paul J Rutgeerts; Ann Gils; William J Sandborn; Séverine Vermeire; Brian G Feagan

doi:10.1136/gutjnl-2014-307883

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Inflammatory bowel disease

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The relationship between infliximab concentrations, antibodies to infliximab and disease activity in Crohn's disease

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Niels Vande Casteele KU Leuven Department of Pharmaceutical and Pharmacological Sciences, Leuven, Belgium Division of Gastroenterology, University of California San Diego, La Jolla, California, USA Robarts Clinical Trials, Western University, London, Ontario, Canada PubMed articles Google scholar articles
Reena Khanna Robarts Clinical Trials, Western University, London, Ontario, Canada PubMed articles Google scholar articles
Barrett G Levesque Division of Gastroenterology, University of California San Diego, La Jolla, California, USA Robarts Clinical Trials, Western University, London, Ontario, Canada PubMed articles Google scholar articles
Larry Stitt Robarts Clinical Trials, Western University, London, Ontario, Canada PubMed articles Google scholar articles
G Y Zou Robarts Clinical Trials, Western University, London, Ontario, Canada PubMed articles Google scholar articles
Sharat Singh Prometheus Laboratories, Inc., San Diego, California, USA PubMed articles Google scholar articles
Steve Lockton Prometheus Laboratories, Inc., San Diego, California, USA PubMed articles Google scholar articles
Scott Hauenstein Prometheus Laboratories, Inc., San Diego, California, USA PubMed articles Google scholar articles
Linda Ohrmund Prometheus Laboratories, Inc., San Diego, California, USA PubMed articles Google scholar articles
Gordon R Greenberg University of Toronto, Mount Sinai Hospital, Toronto, Ontario, Canada PubMed articles Google scholar articles
Paul J Rutgeerts KU Leuven Department of Clinical and Experimental Medicine, Leuven, Belgium PubMed articles Google scholar articles
Ann Gils KU Leuven Department of Pharmaceutical and Pharmacological Sciences, Leuven, Belgium PubMed articles Google scholar articles
William J Sandborn Division of Gastroenterology, University of California San Diego, La Jolla, California, USA PubMed articles Google scholar articles
Séverine Vermeire KU Leuven Department of Clinical and Experimental Medicine, Leuven, Belgium PubMed articles Google scholar articles
Brian G Feagan Robarts Clinical Trials, Western University, London, Ontario, Canada PubMed articles Google scholar articles

Correspondence to Brian G Feagan, Department of Medicine, Robarts Research Institute, University of Western Ontario, PO Box 5015, 100 Perth Drive, London, Ontario N6A 5K8, Canada; Brian.Feagan{at}robartsinc.com

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Vande Casteele N, Khanna R, Levesque BG, et al

The relationship between infliximab concentrations, antibodies to infliximab and disease activity in Crohn's disease

Gut 2015;64:1539-1545.

Publication history

Received June 20, 2014
Revised September 3, 2014
Accepted September 26, 2014
First published October 21, 2014.

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October 26, 2017

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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