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Author response: oral contraceptives and Crohn’s disease
  1. Hamed Khalili1,
  2. Andrew T Chan1,2
  1. 1 Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
  2. 2 Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA
  1. Correspondence to Dr Hamed Khalili, Gastrointestinal Unit, Massachusetts General Hospital, 165 Cambridge St., 9th floor, Boston, MA 02114, USA; hkhalili{at}

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We appreciate the suggestion by Dr Rhodes to further evaluate the link between oral contraceptive (OC) use and risk of Crohn's disease according to the anatomical location of disease involvement.1 We agree that a plausible mechanism for the link between OC use and risk of Crohn's disease may be through the effect of oestrogen on subacute thrombosis, leading to the development of multifocal ischaemia and …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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