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Hepatology
Original article
In vivo evidence for ribavirin-induced mutagenesis of the hepatitis E virus genome

Authors

  • Daniel Todt Institute of Experimental Virology, Twincore, Centre for Experimental and Clinical Infection Research; a joint venture between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI), Hannover, Germany PubMed articlesGoogle scholar articles
  • Anett Gisa Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany PubMed articlesGoogle scholar articles
  • Aleksandar Radonic Division of Highly Pathogenic Viruses, Robert-Koch-Institut, Centre for Biological Threats and Special Pathogens, Berlin, Germany PubMed articlesGoogle scholar articles
  • Andreas Nitsche Division of Highly Pathogenic Viruses, Robert-Koch-Institut, Centre for Biological Threats and Special Pathogens, Berlin, Germany PubMed articlesGoogle scholar articles
  • Patrick Behrendt Institute of Experimental Virology, Twincore, Centre for Experimental and Clinical Infection Research; a joint venture between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI), Hannover, Germany Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany PubMed articlesGoogle scholar articles
  • Pothakamuri Venkata Suneetha Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany PubMed articlesGoogle scholar articles
  • Sven Pischke Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany First Medical Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany PubMed articlesGoogle scholar articles
  • Birgit Bremer Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany PubMed articlesGoogle scholar articles
  • Richard J P Brown Institute of Experimental Virology, Twincore, Centre for Experimental and Clinical Infection Research; a joint venture between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI), Hannover, Germany PubMed articlesGoogle scholar articles
  • Michael P Manns Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany German Center for Infectious Disease Research (DZIF), Partnersite Hannover-Braunschweig, Germany PubMed articlesGoogle scholar articles
  • Markus Cornberg Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany German Center for Infectious Disease Research (DZIF), Partnersite Hannover-Braunschweig, Germany PubMed articlesGoogle scholar articles
  • C Thomas Bock Division of Viral Gastroenteritis, Hepatitis Pathogens and Enteroviruses, Department of Infectious Diseases, Robert-Koch-Institut, Berlin, Germany PubMed articlesGoogle scholar articles
  • Eike Steinmann Institute of Experimental Virology, Twincore, Centre for Experimental and Clinical Infection Research; a joint venture between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI), Hannover, Germany PubMed articlesGoogle scholar articles
  • Heiner Wedemeyer Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany German Center for Infectious Disease Research (DZIF), Partnersite Hannover-Braunschweig, Germany PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Heiner Wedemeyer, Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, 30625 Hannover, Germany; Wedemeyer.Heiner{at}mh-hannover.de
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Citation

Todt D, Gisa A, Radonic A, et al
In vivo evidence for ribavirin-induced mutagenesis of the hepatitis E virus genome
Gut 2016;65:1733-1743.

Publication history

  • Received October 30, 2015
  • Revised March 24, 2016
  • Accepted April 10, 2016
  • First published May 24, 2016.
Online issue publication 
September 08, 2016

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/